Engineered patient-derived organotypic bone model for multimodal characterization of donor-specific response to therapy
Anke M. de Leeuw, Chris Steffi, Gian Nutal Schädli, Amit Singh, Pei Jin Lim, Marianne Rohrbach, Cecilia Giunta, Matthias Rüger, Ralph Müller
The paper develops a 3D bioprinted bone model from patient-derived cells to study donor-specific therapeutic responses to DKK1Ab in osteogenesis imperfecta.
bioRxiv · Apr 17, 2025 · PreprintBioengineering