Sumit Biswas

This study shows that lipid nanoparticles can deliver mRNA to various inner retinal cell types, with higher efficiency in degenerate retinas and when the inner limiting membrane is removed.

The paper generates a Kcnv2 E151X mouse model to study KCNV2-associated retinal dystrophy and shows it replicates key functional and structural features of the human disease.

This study examines how native and optogenetic visual responses interact in mice with residual vision, finding distinct electroretinography signatures and asynchronous cortical responses.