A configurable model of the synaptic proteome reveals the molecular mechanisms of disease co-morbidity.
Oksana Sorokina, Colin Mclean, Mike D. R. Croning, Katharina F. Heil, Emilia Wysocka, Xin He, David C. Sterratt, Seth G. N. Grant, T. Ian Simpson, J Douglas Armstrong
The paper constructs a configurable synaptic proteome network model to analyze molecular mechanisms of disease co-morbidity by integrating proteomic and interaction data.
bioRxiv · Oct 27, 2020 · PreprintSystems Biology