Author

Sebastián Leptihn

University of Southern DenmarkORCID 0000-0002-4847-4622Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Belinda LohiD· 3 shared Xiaoting HuaiD· 2 shared Bartłomiej GrygorcewicziD· 1 shared Jiayuan CheniD· 1 shared Patrycja OlszewskaiD· 1 shared Prasanth ManohariD· 1 shared Rayhaan Gerard PaisiD· 1 shared W.S. CheniD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersBioinformatics

Belinda LohORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Sequential Use of Two Capsule-Targeting Klebsiella Phages Reveals Order-Dependent Efficacy and Distinct Resistance Pathways in vitro and in vivo

Zhanybek Selpiev, Patrycja Olszewska, Bartłomiej Grygorcewicz, Sebastián Leptihn, Belinda Loh

This study shows that sequential use of two K1-targeting phages can improve efficacy against Klebsiella pneumoniae by exploiting resistance-virulence trade-offs and avoiding shared resistance pathways.

bioRxiv · Jun 10, 2026 · PreprintMicrobiology

TattleTail: A Pyocin Prediction Tool

Rayhaan Gerard Pais, W.S. Chen, Sebastián Leptihn, Xiaoting Hua, Belinda Loh

TattleTail identifies pyocin-encoding gene clusters in Pseudomonas aeruginosa genomes, distinguishing them from prophages by lacking canonical phage features.

bioRxiv · Mar 27, 2026 · PreprintBioinformatics

A Biological Inventory of Prophages in A. baumannii Genomes Reveal Distinct Distributions in Classes, Length and Genomic Positions

Belinda Loh, Jiayuan Chen, Prasanth Manohar, Yunsong Yu, Xiaoting Hua, Sebastián Leptihn

The paper analyzes prophage distribution in A. baumannii genomes, finding two common families, variable prophage numbers, and AMR gene carriage in prophages.

Frontiers in Microbiology · Dec 2, 2020Peer-reviewedBioinformatics