Lab-on-a-chip device integrating a human stem cell-based blood-brain barrier model with neural organoids for translational research
Judit P. Vigh, Anna E. Kocsis, Ana Raquel Santa-Maria, Nóra Kucsápszky, Emese Bató, Silvia Bolognin, Jens Christian Schwamborn, András Kincses, Sándor Valkai, Anikó Szecskó, Szilvia Veszelka, Mária Mészáros, Gergő Porkoláb, Thi Ha My Phan, Jeng‐Shiung Jan, , Fruzsina R. Walter
This paper develops a lab-on-a-chip system integrating a human BBB model with neural organoids to study BBB function and nanoparticle transport, showing BBB integrity and nanoparticle entry into neural tissue.
bioRxiv · Sep 17, 2026 · PreprintCell Biology