Genome-first detection of emerging resistance to novel therapeutic agents for SARS-CoV-2
Manon Ragonnet‐Cronin, Rungtiwa Nutalai, Jiandong Huo, Aiste Dijokaite-Guraliuc, Raksha Das, Aekkachai Tuekprakhon, Piyada Supasa, Chang Liu, Muneeswaran Selvaraj, Natalie Groves, Hassan B. Hartman, Nicholas A.F. Ellaby, J. Mark Sutton, Mohammad W. Bahar, Daming Zhou, , Sakib Rokadiya
The paper identifies mutations in SARS-CoV-2 variants that confer resistance to monoclonal antibodies by analyzing genomic data and validating their impact on antibody neutralization.
bioRxiv · Jul 14, 2022 · PreprintGenetics