John Jun

The paper identifies six molecular subtypes of GIST using single nucleus RNA sequencing and correlates them with clinicopathologic features and clinical outcomes.

The paper evaluates ssGSEA's performance on scRNA-seq data, finds it unreliable due to sparsity, and identifies UCell as more robust for pseudobulk analysis.

EpiMix identifies differential DNA methylation in large cohorts with higher sensitivity than existing methods, revealing novel epigenetic mechanisms in childhood food allergy and lung cancer.