Author

Mercedes Novo

Universidade de Santiago de CompostelaORCID 0000-0002-4869-289XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1

Frequent Co-Authors

Álvaro J. AranaiD· 1 shared Ana Seijas· 1 shared Diego Cora· 1 shared Laura Sanchez· 1 shared Wajih Al‐SoufiiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiochemistry

Álvaro J. AranaORCID

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1 paper

Recent·Most cited

BiochemistryInternational Journal of Biological MacromoleculesPeer-reviewedMay 9, 2026

Critical role of Cas9 aggregation on in vitro DNA cleavage

Diego Cora, Ana Seijas, Wajih Al‐Soufi…·Mercedes Novo

This study shows that Cas9 aggregation reduces in vitro DNA cleavage efficiency and highlights strategies to mitigate aggregation for better CRISPR/Cas9 performance.

1 citation

experimental assay

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