Author

Simona G. Huwiler

University of ZurichORCID 0000-0002-4876-9308Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:clustering· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Bernd RoschitzkiiD· 2 shared Andreas DiepoldiD· 1 shared Denis JankoviD· 1 shared Florian LindneriD· 1 shared Jonas GrossmanniD· 1 shared Lara M. HofackeriD· 1 shared Ljiljana MihajloviciD· 1 shared Ove Ch. MattmanniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersEvolutionary Biology

Bernd RoschitzkiORCID

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3 papers

Recent·Most cited

Outer membrane changes enable evolutionary escape from bacterial predation

Subham Mridha, Ove Ch. Mattmann, Sarah-Luise Loose, Saskia Isele, Bernd Roschitzki, Rolf Kümmerli, Simona G. Huwiler

This study shows that Escherichia coli can evolve resistance to the predatory bacterium Bdellovibrio bacteriovorus through changes in outer membrane proteins, with fitness costs.

The ISME Journal · Jan 1, 2026Peer-reviewedEvolutionary Biology

Modulating gene expression and protein secretion in the bacterial predator Bdellovibrio bacteriovorus

Ljiljana Mihajlovic, Lara M. Hofacker, Florian Lindner, Priyanikha Jayakumar, Andreas Diepold, Simona G. Huwiler

This paper develops a genetic toolkit for Bdellovibrio bacteriovorus to modulate gene expression and protein secretion, enhancing its potential for bioengineering and research applications.

PLoS Genetics · Nov 10, 2025Peer-reviewedMicrobiology

Quantitative proteome of bacterial periplasmic predation reveals a prey damaging protease

Ting Fung Lai, Denis Jankov, Jonas Grossmann, Bernd Roschitzki, Simona G. Huwiler

The paper quantifies the proteome of Bdellovibrio bacteriovorus during predation of E. coli, identifying a protease involved in prey damage and exit.

Communications Biology · Oct 22, 2025Peer-reviewedMicrobiology