Author

Subham Mridha

University of PennsylvaniaORCID 0000-0002-3120-6410Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Bernd RoschitzkiiD· 1 shared Daivon D Brown· 1 shared Ellie N Hulit· 1 shared Jeffrey R. MaslankaiD· 1 shared Joshua E. DennyiD· 1 shared Kevin S MearsiD· 1 shared Md Zahidul Alam· 1 shared Michael C. AbtiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperEvolutionary Biology

Bernd RoschitzkiORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintSep 23, 2026

Immunotherapy restores therapeutic efficacy of fecal microbiome transplants to treat Clostridioides difficile

Subham Mridha, Md Zahidul Alam, Joshua E. Denny…·Michael C. Abt

This study shows that IL-10 signaling deficiency impairs FMT engraftment and C. difficile resolution, and that IL-10 immunotherapy can restore FMT efficacy in mice.

DOI 10.64898/2026.09.17.752434

mouseexperimental assay

𝕏 PostBluesky

Evolutionary BiologyThe ISME JournalPeer-reviewedJan 1, 2026

Outer membrane changes enable evolutionary escape from bacterial predation

Subham Mridha, Ove Ch. Mattmann, Sarah-Luise Loose…·Simona G. Huwiler

This study shows that Escherichia coli can evolve resistance to the predatory bacterium Bdellovibrio bacteriovorus through changes in outer membrane proteins, with fitness costs.

1 citation

E. coliproteomics

𝕏 PostBluesky