Author

João Marcos Fagundes Silva

Consejo Superior de Investigaciones CientíficasORCID 0000-0002-4880-031XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:Drosophila· 1 Organism:human· 1 Organism:virus· 1

Frequent Co-Authors

Santiago F. ElenaiD· 3 shared Carlos Peña-GarayiD· 1 shared Fernando Lucas de MeloiD· 1 shared José Ángel OteoiD· 1 shared María J. Olmo-UcedaiD· 1 shared Paul E. TurneriD· 1 shared Tatsuya NagataiD· 1 shared Valerie J. MorleyiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 12 mutual co-author links

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3 shared papersSystems Biology

Santiago F. ElenaORCID

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3 papers

Recent·Most cited

Taylor's power law rules the dynamics of allele frequencies during viral evolution in response to host changes

João Marcos Fagundes Silva, María J. Olmo-Uceda, Valerie J. Morley, Paul E. Turner, Santiago F. Elena

This study examines how host changes affect viral evolution by analyzing allele frequency dynamics and finding that Taylor's power law governs mutation distribution during host replacement.

Journal of The Royal Society Interface · Jul 1, 2025Peer-reviewedEvolutionary Biology

System and transcript dynamics of cells infected with severe acute respiratory syndrome virus 2 (SARS-CoV-2)

João Marcos Fagundes Silva, José Ángel Oteo, Carlos Peña-Garay, Santiago F. Elena

The paper analyzes SARS-CoV-2 infected cell gene expression dynamics using statistical methods, finding biphasic patterns and gene-specific stability/dependence behaviors.

PLOS complex systems. · Nov 5, 2024Peer-reviewedSystems Biology

Heterogeneity in the response of different subtypes of Drosophila melanogaster enteroendocrine cells to viral infections

João Marcos Fagundes Silva, Tatsuya Nagata, Fernando Lucas de Melo, Santiago F. Elena

The paper uses scRNA-seq to compare how two viruses affect enteroendocrine cells in Drosophila, showing subtype-specific replication strategies and gene expression changes.

bioRxiv · Jul 1, 2020 · PreprintSystems Biology