Cell BiologybioRxivPreprint
The Impact of Methylglyoxal and SOD1 Mutation on TDP-43 Interaction in ALS Proteinopathy
Gabriela Delaqua Ribeiro, Daniela Dias Queiroz, José Raphael Monteiro Neto…·Elis C. A. Eleuthério
This study investigates how methylglyoxal and G93A SOD1 mutation affect TDP-43 interaction, showing increased cytosolic TDP-43 aggregation and reduced cell viability.
DOI 10.1101/2025.09.25.678586