Author

Sarah Aldred

University of BirminghamORCID 0000-0002-4889-8716Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Adele Ludlam· 1 shared Ali MazaheriiD· 1 shared Connor DunleavyiD· 1 shared Dong Hee KimiD· 1 shared Eric James HilliD· 1 shared H. Rheinallt ParriiD· 1 shared J. Brown· 1 shared Jane E. RaymondiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Adele Ludlam

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Altered metabolic function induced by amyloid-beta oligomers and PSEN1-mutations in iPSC-derived astrocytes.

Richard J. Elsworthy, Mattéa J. Finelli, Sarah Aqattan, Connor Dunleavy, Marianne C. King, Adele Ludlam, S. L. Allen, S. Prosser, Robert E. Chen, Sandra Martínez‐Jarquín, Dong Hee Kim, J. Brown, H. Rheinallt Parri, Sarah Aldred, Eric James Hill

This study shows that astrocytes from early-onset familial Alzheimer's disease patients exhibit altered metabolism and gliosis, suggesting early metabolic changes may contribute to disease progression.

bioRxiv · Aug 23, 2023 · PreprintNeuroscience

Unique Neurophysiological Vulnerability of Visual Attention Networks to Acute Inflammation

Leonie J. T. Balter, Jos A. Bosch, Sarah Aldred, Mark Trehane Drayson, Jet Veldhuijzen Zanten, Suzanne Higgs, Jane E. Raymond, Ali Mazaheri

This study shows that acute mild inflammation from typhoid vaccination alters neurophysiological processes related to attention, specifically increasing alpha suppression in alerting without affecting behavior.

bioRxiv · Apr 4, 2019 · PreprintNeuroscience