Author

S. L. Allen

University Hospitals Birmingham NHS Foundation Trust

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:plant (other)· 2 Approach:statistical model· 2 Organism:Arabidopsis· 1 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

D. Ortiz-Barrientos· 2 shared M. E. James· 2 shared A. Sebastian· 1 shared Adele Ludlam· 1 shared C. A. Beveridge· 1 shared C. Koh· 1 shared Connor DunleavyiD· 1 shared Dong Hee KimiD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersEvolutionary Biology

D. Ortiz-Barrientos

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Author profile →

4 papers

Recent·Most cited

Altered metabolic function induced by amyloid-beta oligomers and PSEN1-mutations in iPSC-derived astrocytes.

Richard J. Elsworthy, Mattéa J. Finelli, Sarah Aqattan, Connor Dunleavy, Marianne C. King, Adele Ludlam, S. L. Allen, S. Prosser, Robert E. Chen, Sandra Martínez‐Jarquín, Dong Hee Kim, J. Brown, H. Rheinallt Parri, Sarah Aldred, Eric James Hill

This study shows that astrocytes from early-onset familial Alzheimer's disease patients exhibit altered metabolism and gliosis, suggesting early metabolic changes may contribute to disease progression.

bioRxiv · Aug 23, 2023 · PreprintNeuroscience

Adaptive divergence in shoot gravitropism creates hybrid sterility in an Australian wildflower

M. J. Wilkinson, F. Roda, G. M. Walter, M. E. James, R. Nipper, J. Walsh, S. L. Allen, H. L. North, C. A. Beveridge, D. Ortiz-Barrientos

This study shows that adaptive divergence in shoot gravitropism contributes to hybrid sterility in Senecio lautus, linking local adaptation to speciation through reproductive isolation.

bioRxiv · Mar 21, 2021Evolutionary Biology

Highly replicated evolution of parapatric ecotypes

M. E. James, H. Arenas-Castro, J. S. Groh, S. L. Allen, J. Engelstaedter, D. Ortiz-Barrientos

This study shows that selection can repeatedly create similar ecotypes despite low gene flow between parapatric populations of Senecio lautus.

bioRxiv · Feb 5, 2020Evolutionary Biology

Artificial selection finds new hypotheses for the mechanism of Wolbachia-mediated dengue blocking in mosquitoes

S. A. Ford, I. Albert, S. L. Allen, S. Chenoweth, M. Jones, C. Koh, A. Sebastian, L. T. Sigle, E. A. McGraw

The paper uses artificial selection to identify genetic variations linked to Wolbachia-mediated dengue blocking in mosquitoes and proposes hypotheses about the underlying mechanisms.

bioRxiv · Nov 25, 2019Evolutionary Biology