ImmunologyPLoS PathogensPeer-reviewed
Directed evolution of a stem-helix targeting antibody enables MERS-CoV cross-neutralization through enhanced binding affinity
Pan-Pan Zhou, Meng Yuan, Yuexiu Zhang…·Raiees Andrabi
This paper describes the directed evolution of an antibody to enhance its binding affinity for MERS-CoV, resulting in cross-neutralization against multiple betacoronaviruses.
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