Engineering single pan-specific ubiquibodies for targeted degradation of all forms of endogenous ERK protein kinase
Erin A. Stephens, Morgan B. Ludwicki, Bunyarit Meksiriporn, Mingji Li, Tianzheng Ye, Connor Monticello, Katherine J. Forsythe, Lutz Kummer, Pengbo Zhou, Andreas Plückthun, Matthew P. DeLisa
This paper describes the engineering of ubiquibodies (uAbs) that degrade all forms of endogenous ERK1/2 protein kinase in multiple cell lines.
ACS Synthetic Biology · Aug 16, 2021Peer-reviewedSynthetic Biology