Cancer BiologybioRxivPreprint
Membrane localisation and checkpoint blockade enhance xenoantigen delivery to redirect pre-existing immunity against tumours
Sylvie Hauert, Fuxin Zhou, Justas Šidiškis…·Priscilla S. Briquez
This study shows that membrane-localized xenoantigens enhance CD4+ T cell responses and improve anti-PD-1 therapy efficacy in pre-immunized mice, using OVA and VZV gE antigens.
DOI 10.64898/2026.03.01.708859