Molecular unbalances between striosome and matrix compartments characterize the pathogenesis of Huntington's disease model mouse
Ryoma Morigaki, Tomoko Yoshida, Joji Fujikawa, Jill R. Crittenden, Ann M. Graybiel
The paper uses machine learning to analyze striosome and matrix compartments in Huntington's disease model mice, revealing age-related molecular differences that may explain disease pathogenesis.
bioRxiv · Jul 20, 2025 · PreprintNeuroscience