BiophysicsComputational and Structural Biotechnology JournalPeer-reviewed
Replacement of a single residue in an antibody completely abolishes cognate antigen binding, as predicted by theoretical methods
Marvin Scherlo, Adrian Höveler, Marvin Mann…·Carsten Kötting
The paper validates a computational prediction of an antibody mutation that abolishes antigen binding using experimental methods, demonstrating its utility in Alzheimer's disease diagnostics.
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