Author

Sophie E. Holmes

Yale UniversityORCID 0000-0002-4929-1932Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Organism:human· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Adam P. MeccaiD· 1 shared Christopher H. van DyckiD· 1 shared David MatuskeyiD· 1 shared Deepak Cyril D’SouzaiD· 1 shared Faranak Ebrahimian SadabadiD· 1 shared Irina EsterlisiD· 1 shared Jean‐Dominique GallezotiD· 1 shared Mahsa MayeliiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Adam P. MeccaORCID

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1 paper

Recent·Most cited

Optimized reference region and the effect on test-retest reliability and detection of Parkinson's disease with UCB-J.

Nikkita Khattar, David Matuskey, Jean‐Dominique Gallezot, Mika Naganawa, Sophie E. Holmes, Faranak Ebrahimian Sadabad, Mahsa Mayeli, Irina Esterlis, Christopher H. van Dyck, Adam P. Mecca, Deepak Cyril D’Souza, Nabeel Nabulsi, Sjoerd J. Finnema, Yiyun Henry Huang, Richard E. Carson, Takuya Toyonaga

This study evaluates an alternative reference region method for [11C]UCB-J to improve test-retest reliability and Parkinson's disease detection, finding reduced variability and greater effect sizes with a 10mL white matter reference region.

bioRxiv · Oct 15, 2025 · PreprintNeuroscience