Richard C. Law

Robustness of mitochondrial biogenesis and respiration explain aerobic glycolysis

The paper explains aerobic glycolysis as a result of mitochondrial respiration saturation and decoupling of mitochondrial biogenesis from other cellular processes.

Accurate and rapid determination of metabolic flux by deep learning of isotope patterns

This paper introduces ML-Flux, a deep learning framework for accurately and rapidly determining metabolic flux from isotope patterns, outperforming existing methods in speed and accuracy.

A parallel glycolysis supports rapid adaptation in dynamic environments

The paper identifies that the Entner-Doudoroff pathway provides a metabolic advantage in dynamic nutrient environments by enabling faster response times during nutrient upshifts.