Author

Alexander Ernst

University of BernORCID 0000-0002-4956-315XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:zebrafish· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Nadia MercaderiD· 3 shared Ines Joao MarquesiD· 2 shared Prateek AroraiD· 2 shared Adolfo Odriozola· 1 shared Andréj Vianin· 1 shared Andrés Sanz-MorejóniD· 1 shared Andrew C. OatesiD· 1 shared Ayisha Marwa MPiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersDevelopmental Biology

Nadia MercaderORCID

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3 papers

Recent·Most cited

Developmental BiologyiSciencePeer-reviewedNov 19, 2024

Spns1-dependent endocardial lysosomal function drives valve morphogenesis through Notch1-signaling.

Myra Noemi Chávez, Prateek Arora, Marco Meer…·Nadia Mercader

This study identifies a role for Spns1-dependent lysosomal function in endocardial cells during cardiac valve development, showing its impact on Notch1 signaling and valve morphology.

3 citations

zebrafishbulk RNA-seq

𝕏 PostBluesky

Developmental BiologyScientific ReportsPeer-reviewedOct 9, 2023

Identification of side effects of COVID-19 drug candidates on embryogenesis using an integrated zebrafish screening platform

Alexander Ernst, Indre Piragyte, Ayisha Marwa MP…·Nadia Mercader

The paper evaluates the effects of 162 FDA-approved drugs on zebrafish embryogenesis and immune response to SARS-CoV-2 spike protein, identifying potential developmental side effects.

5 citations

zebrafishspatial transcriptomics

𝕏 PostBluesky

Developmental BiologybioRxivPreprintJul 6, 2021

Downregulation of WT1 transcription factor gene expression is required to promote myocardial fate

Ines Joao Marques, Alexander Ernst, Prateek Arora…·Nadia Mercader

The paper shows that sustained WT1 expression impairs cardiomyocyte maturation and leads to their transformation into epicardial cells in zebrafish.

DOI 10.1101/2021.07.06.451274

zebrafishATAC-seq

𝕏 PostBluesky