Prateek Arora

This study shows that paternal cardiac injury in vertebrates triggers inflammatory signals to the gonads, leading to intergenerational cardiac effects in offspring.

The paper identifies essential cardiac enhancer modules and regulatory mechanisms governing heart development, revealing resilience in cis-regulatory architectures and the role of Hand2 upstream regulatory intervals.

Paternal cardiac injury in mice improves offspring cardiac recovery and function through heritable changes.

This study identifies a role for Spns1-dependent lysosomal function in endocardial cells during cardiac valve development, showing its impact on Notch1 signaling and valve morphology.

The paper shows that sustained WT1 expression impairs cardiomyocyte maturation and leads to their transformation into epicardial cells in zebrafish.