Ines Joao Marques

This study shows that paternal cardiac injury in vertebrates triggers inflammatory signals to the gonads, leading to intergenerational cardiac effects in offspring.

The paper identifies essential cardiac enhancer modules and regulatory mechanisms governing heart development, revealing resilience in cis-regulatory architectures and the role of Hand2 upstream regulatory intervals.

This study identifies a role for Spns1-dependent lysosomal function in endocardial cells during cardiac valve development, showing its impact on Notch1 signaling and valve morphology.

The paper shows that sustained WT1 expression impairs cardiomyocyte maturation and leads to their transformation into epicardial cells in zebrafish.

The paper identifies a subset of pre-existent sox10+ cardiomyocytes in adult zebrafish that expand after injury and are crucial for cardiac regeneration.