Author

William Letsou

St. Jude Children's Research HospitalORCID 0000-0002-4969-2330Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1 Assay:GWAS summary statistics· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Cindy ImiD· 2 shared Fan WangiD· 2 shared Leslie L. RobisoniD· 2 shared Wonjong MooniD· 2 shared Yadav SapkotaiD· 2 shared Yutaka YasuiiD· 2 shared Jessica L. BaedkeiD· 1 shared Zhaoming WangiD· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Cindy ImORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicineCancer ResearchPeer-reviewedNov 9, 2022

Genome-wide Analysis of Rare Haplotypes Associated with Breast Cancer Risk: Discovery, Replication, and Generalizability Evaluation

Fan Wang, Wonjong Moon, William Letsou…·Yutaka Yasui

This study identifies 13 rare haplotypes associated with increased breast cancer risk using genome-wide haplotype-BCa association analysis in UK Biobank data, with partial generalizability in an independent cohort.

7 citations

humanwhole-genome sequencing

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Genetic & Genomic MedicinemedRxivPreprintOct 21, 2022

Potential Misrepresentation of Inherited Breast Cancer Risk by Common Germline Alleles

William Letsou, Fan Wang, Wonjong Moon…·Yutaka Yasui

The paper identifies rare risk haplotypes associated with breast cancer that may misrepresent risk through common alleles, challenging the polygenic model.

DOI 10.1101/2022.10.21.22281361

humanGWAS summary statistics

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