Functional interplay between condensin I and topoisomerase IIα in single-molecule DNA compaction
Yuko Tsubota, Keishi Shintomi, Kazuhisa Kinoshita, Yuki Masahara-Negishi, Yuuki Aizawa, Masami Shima, Tatsuya Hirano, Tomoko Nishiyama
This study shows how condensin I and topoisomerase IIα work together to compact DNA into stable structures at the single-molecule level.
Nature Communications · Aug 6, 2025Peer-reviewedMolecular Biology