Author

Samuel Wieczorek

Centre National de la Recherche ScientifiqueORCID 0000-0002-5016-1203Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:imputation· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

Thomas BürgeriD· 2 shared Laura FancelloiD· 1 shared Lucas EtourneauiD· 1 shared Nelle VaroquauxiD· 1 shared Quentin Giai GianettoiD· 1 shared Yohann CoutéiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

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6 top collaborators · 9 mutual co-author links

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2 shared papersBioinformatics

Thomas BürgerORCID

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2 papers

Recent·Most cited

BioinformaticsBiostatisticsPeer-reviewedDec 31, 2024

Penalized likelihood optimization for censored missing value imputation in proteomics

Lucas Etourneau, Laura Fancello, Samuel Wieczorek…·Thomas Bürger

The paper introduces Pirat, a method for imputing missing values in proteomics data by modeling instrument limits and peptide correlations, showing improved performance over existing methods.

4 citations

proteomicsstatistical model

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMay 29, 2020

A peptide-level multiple imputation strategy accounting for the different natures of missing values in proteomics data

Quentin Giai Gianetto, Samuel Wieczorek, Yohann Couté, Thomas Bürger

Estimating what fraction of missing proteomics values are missing completely at random lets MCAR- and MNAR-specific imputers be combined; on simulations this beats standard imputation.

59 citations

proteomicsstatistical model

𝕏 PostBluesky