Author

Genzhe Lu

Center for Life SciencesORCID 0000-0002-5025-3175Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:optimal transport· 1 Assay:proteomics· 1

Frequent Co-Authors

Bowen CheniD· 1 shared Chuheng QingiD· 1 shared Chun‐Yu CheniD· 1 shared Guo‐Qiang CheniD· 1 shared Hongrui LiuiD· 1 shared Ji GaoiD· 1 shared Jiale FuiD· 1 shared Lize SuniD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperSynthetic Biology

Bowen ChenORCID

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2 papers

Recent·Most cited

PHF1 compartmentalizes PRC2 at target loci via phase separation

Genzhe Lu, Pilong Li

This study shows PHF1 forms phase-separated condensates that recruit PRC2 to target loci, facilitating H3K27me3 deposition and transcription repression.

bioRxiv · Oct 20, 2022 · PreprintMolecular Biology

Regulating enzymatic reactions in Escherichia coli utilizing light-responsive cellular compartments based on liquid-liquid phase separation

Zikang Huang, Lize Sun, Genzhe Lu, Hongrui Liu, Zihan Zhai, Site Feng, Ji Gao, Chun‐Yu Chen, Chuheng Qing, Meng Fang, Bowen Chen, Jiale Fu, Xuan Wang, Guo‐Qiang Chen

This paper introduces PhASE, a system for dynamically controlling enzymatic reactions in E. coli using light-responsive compartments formed by liquid-liquid phase separation, showing enhanced reaction efficiency.

bioRxiv · Nov 26, 2020 · PreprintSynthetic Biology