Author

Alexander Ploner

Karolinska InstitutetORCID 0000-0002-5042-8326Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Organism:human· 1

Frequent Co-Authors

Brandon J. CoombesiD· 1 shared Dylan M. WilliamsiD· 1 shared Joanna M. BiernackaiD· 1 shared Jonas Filip LudvigssoniD· 1 shared Karin WirdefeldtiD· 1 shared Nancy L. PederseniD· 1 shared Sarah E. BergeniD· 1 shared Xiaoying KangiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 18 mutual co-author links

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1 shared paperGenetics

Brandon J. CoombesORCID

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2 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintJan 13, 2022

Genetic overlap between Parkinson disease and inflammatory bowel disease

Xiaoying Kang, Alexander Ploner, Yunzhang Wang…·Karin Wirdefeldt

This study identifies genetic correlations and shared loci between Parkinson disease and inflammatory bowel disease subtypes, highlighting immune-related pathways.

2 citations

humanGWAS summary statistics

𝕏 PostBluesky

GeneticsGenetic EpidemiologyPeer-reviewedJul 21, 2020

A principal component approach to improve association testing with polygenic risk scores

Brandon J. Coombes, Alexander Ploner, Sarah E. Bergen, Joanna M. Biernacka

This paper introduces a principal component approach to improve association testing with polygenic risk scores by reducing type I error and improving power compared to permutation tests and a priori parameter selection.

96 citationstop 2%

GWAS summary statisticsstatistical model

𝕏 PostBluesky