Author

Matthew C. Mendel

Sangamo BioSciences (United States)ORCID 0000-0002-5070-0561Unclaimed ORCID profile · follow to get notified of new preprints

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Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

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Christopher R. BrowniD· 1 shared Gregory J. CostiD· 1 shared Jessica M. Ong· 1 shared

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2017-2017 · peak 1/yr

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1 shared paperSynthetic Biology

Christopher R. BrownORCID

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1 paper

Recent·Most cited

Synthetic BiologybioRxivPreprintApr 12, 2017

The WPRE Improves Genetic Engineering With Site-Specific Nucleases

Jessica M. Ong, Christopher R. Brown, Matthew C. Mendel, Gregory J. Cost

The paper shows that adding the WPRE element to nuclease mRNA increases expression and chromosomal modification efficiency in human and mouse cells, with added benefits from hypothermic shock.

DOI 10.1101/126904

humanmouse

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