Johanna Geuder

Identification and comparison of orthologous cell types from primate embryoid bodies shows limits of marker gene transferability

The paper identifies and compares orthologous cell types across primate species using scRNA-seq data from embryoid bodies, finding limited transferability of marker genes between species.

CroCoNet: a novel framework for cross-species network analysis reveals POU5F1 (OCT4) rewiring

CroCoNet quantitatively compares gene regulatory networks across species, identifying conserved and diverged modules, including POU5F1's rewired network in great apes.

Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development

The paper identifies glycogen metabolism differences in pluripotent cells across species that influence neural differentiation speed.

Prime-seq, efficient and powerful bulk RNA-sequencing

Prime-seq is a bulk RNA-seq method that is four-fold more cost-efficient than TruSeq while maintaining equivalent library complexity, measurement accuracy, and statistical power.

mcSCRB-seq: sensitive and powerful single-cell RNA sequencing

The paper introduces mcSCRB-seq, a new scRNA-seq protocol that improves sensitivity and efficiency through optimized experimental conditions.