Rafał Zaborowski

RNA Masonry assembles RNA fragments into geometrically plausible models using secondary structure constraints and SAXS data.

This paper identifies that normalization techniques for Hi-C data can worsen contact decay bias and proposes using generalized linear models on non-normalized data to better detect differential contacts.

The paper introduces BPscore, a metric for comparing structural chromosome segmentations, showing it satisfies mathematical properties and correlates with gene expression and methylation changes.

DiffTAD provides two statistical methods to detect differential contact frequency in Hi-C Topologically Associating Domains between conditions.