GeneticsNature CommunicationsPeer-reviewed
Whole genome sequencing analysis of the cardiometabolic proteome
Arthur Gilly, Young‐Chan Park, Grace Png…·Eleftheria Zeggini
The paper uses whole-genome sequencing to analyze the genetic architecture of 257 cardiometabolic protein biomarkers, identifying 131 sequence variant associations and constructing polygenic scores that explain up to 45% of protein variation.
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