Author

Victor Alfred

University of SheffieldORCID 0000-0002-5083-8798Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Allan Christian ShawiD· 1 shared Andrew J. GriersoniD· 1 shared Christa G WaltheriD· 1 shared Christopher P WebsteriD· 1 shared Darren A. RobinsoniD· 1 shared Emma F. Smith· 1 shared Guillaume M. HautbergueiD· 1 shared Kurt J. De VosiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Allan Christian ShawORCID

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1 paper

Recent·Most cited

C9orf72-derived poly-GA DPRs undergo endocytic uptake in iNPC-derived astrocytes and spread to motor neurons

Paolo M. Marchi, Lara Marrone, Laurent Brasseur, Luc Bousset, Christopher P Webster, Marco Destro, Emma F. Smith, Christa G Walther, Victor Alfred, Raffaele Marroccella, Darren A. Robinson, Allan Christian Shaw, Lai Mei Wan, Andrew J. Grierson, Stephen J. Ebbens, , Mimoun Azzouz

This study shows poly-GA DPRs are taken up by astrocytes via endocytosis, spread to motor neurons, and cause axonal swellings through lysosomal dysfunction.

bioRxiv · Oct 11, 2021 · PreprintNeuroscience