Subhasis B. Biswas

Pathogenic impact of ABCA4 missense variants in the structurally uncharacterized ECD1 region: implications for Stargardt disease.

The paper evaluates the pathogenicity of ABCA4 missense variants in the uncharacterized ECD1 region using in silico and in vitro methods, identifying variants that disrupt protein stability and function.

De Novo Design and Computational Validation of a High-Affinity Peptide Inhibitor Targeting the HPV E1-E2 Interface

This paper designs and validates a high-affinity peptide inhibitor targeting the HPV E1-E2 interface using computational methods, showing improved binding affinity and safety.

Design, Expression, and Purification of a Soluble Form of the Retina-Specific Membrane Transporter, ABCA4

This paper designs and purifies a soluble form of ABCA4, a membrane transporter critical for vision, which maintains enzymatic activity without detergent-based purification.