Esther E. Biswas

The paper evaluates the pathogenicity of ABCA4 missense variants in the uncharacterized ECD1 region using in silico and in vitro methods, identifying variants that disrupt protein stability and function.

This paper designs and validates a high-affinity peptide inhibitor targeting the HPV E1-E2 interface using computational methods, showing improved binding affinity and safety.

This paper designs and purifies a soluble form of ABCA4, a membrane transporter critical for vision, which maintains enzymatic activity without detergent-based purification.