Author

Bo Li

Xi’an Jiaotong-Liverpool UniversityORCID 0000-0002-5089-7480Unclaimed ORCID profile · follow to get notified of new preprints

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Bo Li20 papers · Children's Hospital of Philadelphia

Biology Disciplines

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Bioinformatics· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:deep learning· 1 Organism:human· 1 Approach:large language model· 1 Assay:scRNA-seq· 1 Approach:transformer / foundation model· 1

Frequent Co-Authors

Huaicheng SuniD· 2 shared Wanghao Jiang· 2 shared Feng Zhu· 1 shared Hao Yang· 1 shared Hongning ZhangiD· 1 shared Lingyan ZhengiD· 1 shared Mingkun LuiD· 1 shared Minjie MouiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPharmacology & Toxicology

Huaicheng SunORCID

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2 papers

Recent·Most cited

An AI System for Autonomous Algorithm Evolution in Drug Development

Zhimeng Zhou, Yang Nan, Minjie Mou, Yuntao Qian, Yixiu Liu, Zhengyu Zuo, Hao Yang, Weixian Xu, Bo Li, Wanghao Jiang, Yanlin Ren, Yang Liao, Yimeng Wang, Yingxia Li, Qingxia Yang, , Feng Zhu

DrugEvolve autonomously evolves algorithms across drug development stages, improving performance on benchmark tests and showing generalizability across data modalities.

bioRxiv · Aug 20, 2026 · PreprintPharmacology & Toxicology

A Multi-modal LLM-Knowledge Fusion Framework for Predicting Single-cell Genetic Perturbation Effects

Mingkun Lu, Nanxin You, Hongning Zhang, Lingyan Zheng, Bo Li, Wanghao Jiang, Y Zhang, Huaicheng Sun, Y Zhou

scPert predicts single-cell transcriptomic responses to genetic perturbations by integrating large language model embeddings and biological knowledge, improving accuracy in both single-gene and combinatorial perturbations.

bioRxiv · Apr 28, 2026 · PreprintBioinformatics