NeuroscienceAdvanced SciencePeer-reviewed
Chronic potentiation of metabotropic glutamate receptor 2 with a nanobody accelerates amyloidogenesis in Alzheimer's disease.
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo G Alenda…·Philippe Rondard
This study shows that chronic activation of mGlu2 receptors with a nanobody accelerates amyloid formation and worsens memory deficits in Alzheimer's disease models.
DOI 10.1002/advs.202523791