Cancer BiologybioRxivPreprint
Functional Deorphanization of Tumor-reactive TCRs Uncovers a Landscape of Shared, Immune Dominant Antigens across Cancers
Orian Bricard, Razgar Seyed Rahmani, Frederik Peeters…·Diether Lambrechts
This study introduces TWISTAR, a platform to identify tumor-reactive TCRs and their antigens, revealing shared immunogenic targets across cancers and immune dominance.