Edward W. Green

This study introduces TWISTAR, a platform to identify tumor-reactive TCRs and their antigens, revealing shared immunogenic targets across cancers and immune dominance.

The paper identifies CD4+ tissue-resident memory T-cells as markers of response to immune checkpoint inhibition in high-grade glioma.

This paper introduces a chromosomally integrated yeast surface display system for scalable, quantitative antibody profiling and serological assays.

This study identifies rare tumor-reactive T cells and conserved antigen repertoires in multiple myeloma and acute myeloid leukemia, developing a TCR fitness model to predict immunotherapy response.

makeTCR provides a modular platform for rapid, scalable, single-step TCR synthesis and validation, enabling functional testing within 48 hours.

T-FINDER identifies T cell epitopes and their cognate receptors by analyzing HLA-presented peptides, demonstrating its utility in multiple diseases.

This study describes a patient with diffuse midline glioma who achieved remission after vaccination with an H3K27M peptide vaccine, showing robust T and B cell responses across diverse HLA alleles.

ARDitox predicts TCR off-target binding using computational immunology and AI, identifying cross-reactive epitopes in cancer and viral targets.

This study shows that the circadian clock gene bmal1 is necessary for circatidal rhythms in Eurydice pulchra, while other negative regulators are not.