Cancer BiologybioRxivPreprint
MYD88 mutations in clonal hematopoiesis promote inflammation and hematopoietic stem cell expansion
Jennifer Yeung, Sophia Y Philbrook, Emma E. Uible…·Daniel T. Starczynowski
This study shows MYD88 mutations in clonal hematopoiesis drive inflammation and HSPC expansion by activating NF-κB pathways and promoting myeloid bias.