Author

Courtnee A. Clough

Cincinnati Children's Hospital Medical CenterORCID 0000-0002-7859-7252Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Anja R. OllodartiD· 1 shared Arletta Lozanski· 1 shared Bonita J. BreweriD· 1 shared Christopher R. L. LargeiD· 1 shared Daniel T. StarczynowskiiD· 1 shared Elizabeth X. KwaniD· 1 shared Emma E. UibleiD· 1 shared Erin K. HertleiniD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperGenetics

Anja R. OllodartORCID

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2 papers

Recent·Most cited

MYD88 mutations in clonal hematopoiesis promote inflammation and hematopoietic stem cell expansion

Jennifer Yeung, Sophia Y Philbrook, Emma E. Uible, Lynn H. Lee, Kwangmin Choi, Puneet Agarwal, Courtnee A. Clough, Pravin Patel, Kathryn A. Wikenheiser‐Brokamp, Kathleen M. Hueneman, Hans Christian Reinhardt, Tzyy-Jye Doong, Arletta Lozanski, Gerard Lozanski, Tamanna Zohra Haque, , Daniel T. Starczynowski

This study shows MYD88 mutations in clonal hematopoiesis drive inflammation and HSPC expansion by activating NF-κB pathways and promoting myeloid bias.

bioRxiv · Jun 19, 2025 · PreprintCancer Biology

Phenotypic and genotypic consequences of CRISPR/Cas9 editing of the replication origins in the rDNA of Saccharomyces cerevisiae

Joseph C. Sanchez, Anja R. Ollodart, Christopher R. L. Large, Courtnee A. Clough, Gina M. Alvino, Mitsuhiro Tsuchiya, Matthew M. Crane, Elizabeth X. Kwan, Matt R. Kaeberlein, Maitreya J. Dunham, M. K. Raghuraman, Bonita J. Brewer

This study edits rDNA replication origins in yeast using CRISPR/Cas9, revealing growth and lifespan consequences of such modifications.

Genetics · Jul 10, 2019Peer-reviewedGenetics