A Cone-Plate Bioreactor for Applying Physiologically Derived Shear Stress Waveforms to Study Endothelial Mechanotransduction and Cardiac Cell Signaling
Matthew C. Watson, Erica Cherry Kemmerling, Lauren Deems Black
This paper introduces a cone-plate bioreactor that applies controlled shear stress to endothelial cells and cardiac tissues, showing increased cell alignment and cardiomyocyte proliferation under pulsatile shear.
bioRxiv · Jun 3, 2026 · PreprintBioengineering