Author

Weiyan Chen

Shanghai Institute of Nutrition and HealthORCID 0000-0002-5101-8839Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Andrew Erich TeschendorffiD· 2 shared Jifan ShiiD· 1 shared Kai KessenbrockiD· 1 shared Kerstin B. MeyeriD· 1 shared Luonan CheniD· 1 shared Samuel MorabitoiD· 1 shared Tariq EnveriD· 1 shared Tiejun LiiD· 1 shared

Activity by Year

2018-2019 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersBioinformatics

Andrew Erich TeschendorffORCID

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2 papers

Recent·Most cited

BioinformaticsCommunications BiologyPeer-reviewedAug 9, 2019

Integrated single-cell potency and expression landscape in mammary epithelium reveals novel bipotent-like cells associated with breast cancer risk

Weiyan Chen, Samuel Morabito, Kai Kessenbrock…·Andrew Erich Teschendorff

The paper introduces LandSCENT, a computational method to identify bipotent-like cells in mammary epithelium, which are associated with breast cancer risk.

53 citations

humanscRNA-seq

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BioinformaticsBriefings in BioinformaticsPeer-reviewedAug 30, 2018

Quantifying Waddington’s epigenetic landscape: a comparison of single-cell potency measures

Jifan Shi, Andrew Erich Teschendorff, Weiyan Chen…·Tiejun Li

The paper compares single-cell potency measures using 9 experiments and 6,600 RNA-Seq profiles, finding that graph entropy of a Markov Chain on a signaling network better estimates potency than other methods.

60 citations

scRNA-seqstatistical model

𝕏 PostBluesky