Tariq Enver

This study models B-cell differentiation and leukaemogenesis using a logical framework to show how mutation timing and order affect disease progression in BCP-ALL.

This paper shows that chemotherapy causes long-term bone marrow dysfunction by impairing hematopoietic stem cells, which can be reversed by mitochondrial-targeted treatment.

The paper introduces SPARCE, a method for multiplexed phosphoproteomic analysis of low cell numbers, demonstrating its effectiveness in quantifying phosphosite changes from 1,000 FACS-sorted cells.

The paper introduces LandSCENT, a computational method to identify bipotent-like cells in mammary epithelium, which are associated with breast cancer risk.

This paper introduces SCENT, a method to estimate single-cell differentiation potency using transcriptomic entropy, validated across 7,000 single-cell RNA-Seq profiles.

This paper discusses challenges and future directions in single-cell analysis, highlighting advances in technologies and computational methods for studying cellular heterogeneity.