BiophysicsbioRxivPreprint
Entropy Changes in Water Networks Promote Protein Denaturation
Yichong Wang, Junlang Liu, Michael M. Peters…·Eugene I. Shakhnovich
This study identifies entropy changes in water networks as a mechanism for ion-induced protein denaturation, revealing an 'inverse hydrophobic effect' that promotes unfolding.
DOI 10.1101/2024.06.12.598657