Cell BiologybioRxivPreprint
CHIP, VCP, and Nucleolar Gatekeepers Remodel the Nucleolus into a Stress-Responsive Proteostasis Hub
Malgorzata J. Piechota, Lilla Biriczová, Konrad Kowalski…·Wojciech Pokrzywa
This paper shows that the nucleolus becomes a stress-responsive proteostasis hub during heat shock, regulated by CHIP, VCP, and gatekeepers like NOL6 and WDR55.
DOI 10.1101/2025.10.04.680426