Ritwick Sawarkar

This paper shows that the nucleolus becomes a stress-responsive proteostasis hub during heat shock, regulated by CHIP, VCP, and gatekeepers like NOL6 and WDR55.

This study shows that proteostatic stress in mitochondria impairs mitoribosome biogenesis and translation, leading to respiratory deficiency and mitochondrial DNA loss.

The paper shows that nanoroughness induces a glioblastoma-like phenotype in astrocytes through spheroid formation, MMP2 activation, and gene expression changes.

This study identifies MOK as a kinase regulating microglial inflammatory responses and type-I IFN through Brd4, showing its involvement in ALS pathogenesis.

The paper shows that parts of the TCA cycle operate in the nucleus, challenging the canonical view of metabolic compartmentalization.