Transcriptional dynamics of colorectal cancer risk associated variation at 11q23.1 are correlated with tuft cell abundance and marker expression in silico
Bradley T. Harris, Vidya Rajasekaran, James Peter Blackmur, Alan O’Callaghan, Kevin Donnelly, Maria N Timofeeva, Peter G Vaughan-Shaw, Farhat V. N. Din, Malcolm G. Dunlop, Susan Mary Farrington
The paper investigates the relationship between 11q23.1 eQTL targets and tuft cell abundance using scRNA-seq data, finding a correlation between gene expression and cluster-specific tuft cell markers.
bioRxiv · Mar 29, 2022 · PreprintBioinformatics