Author

Kaarthik Varma

Cornell UniversityORCID 0000-0002-5146-6068Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Charlotta LorenziD· 2 shared Dana MatthiasiD· 2 shared Eric R. DufresneiD· 2 shared Robert W. StyleiD· 2 shared Takumi MatsuzawaiD· 2 shared Teagan BateiD· 2 shared Chase B. Shapiro· 1 shared James P. SethnaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersBiophysics

Charlotta LorenzORCID

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2 papers

Recent·Most cited

Susceptibility and Regulation of Biomolecular Condensates by Solutes

Takumi Matsuzawa, Kaarthik Varma, Teagan Bate, Charlotta Lorenz, Katherine Larina, Jonathan Bauermann, Dana Matthias, Tarik Grubić, Robert W. Style, Michel Olivier Steinmetz, Eric R. Dufresne

The paper introduces susceptibility as a measure of how biomolecular condensates respond to solute perturbations, showing large variations in response across different condensates and solutes.

Proceedings of the National Academy of Sciences · Jul 30, 2026Peer-reviewedBiophysics

Partition Coefficients Reveal Changes in Properties of Low-Contrast Biomolecular Condensates

Kaarthik Varma, Dana Matthias, Chase B. Shapiro, Sullivan Bailey-Darland, Takumi Matsuzawa, Charlotta Lorenz, Teagan Bate, Stephen J. Thornton, Senthilkumar Duraivel, Robert W. Style, James P. Sethna, Eric R. Dufresne

The paper shows that adding small molecules to biomolecular condensates reduces their partition coefficients to physiological levels, revealing changes in their material properties and behavior.

bioRxiv · Feb 23, 2026 · PreprintBiophysics